Quality of Life and Sexual Function 2 Years After Vaginal Surgery for Prolapse

Native tissue vaginal prolapse repair with midurethral sling results in clinically and statistically significant improvements in both generic (SF-36) and condition-specific (PFDI, PFIQ) quality of lif

Effect: improvement; Clinically and statistically significant improvements exceeding MID at all postoperative time points

There were no clinically meaningful or statistically significant differences between uterosacral ligament suspension and sacrospinous ligament fixation for any quality of life measure at any postopera

Effect: null; No clinically meaningful or statistically significant differences between groups (all p>0.05)

Native tissue vaginal prolapse repair with midurethral sling results in clinically and statistically significant improvements in sexual function (PISQ-12) and decreased dyspareunia rates (25% to 16%)

Effect: improvement; PISQ-12 improvement exceeded MID of 6 points at 6 and 12 months, nearly reached MID at 24 months; dyspareunia decreased from 25% to 16%

There were no significant differences between uterosacral ligament suspension and sacrospinous ligament fixation for PISQ-12 scores, overall sexual activity, dyspareunia, de novo dyspareunia, or sexua

Effect: null; No significant differences between surgical groups (all p>0.05)

Among women without baseline dyspareunia (n=134), 6%, 5%, and 10% reported de novo dyspareunia at 6, 12, and 24 months respectively. Only 3 of 19 affected women received treatment by 24 months, and no

Effect: adverse; 10% de novo dyspareunia at 24 months

Body image scores significantly improved from baseline after native tissue vaginal prolapse repair, with clinically significant improvement (exceeding estimated MID of 13.0 on normalized 100-point sca

Effect: improvement; Statistically (p<0.01) and clinically significant improvement from baseline to 6 months (exceeding estimated MID of 13.0)