Natural History

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal gluc

Effect: improvement; 65% reversion rate (IGT to NGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)

Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell funct

Effect: decline; 14% progression rate (NGT to IGT)