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Finding improvement
In a multiethnic cohort of 162 obese youth with baseline impaired glucose tolerance followed prospectively for a mean of 2.9 years with standard-of-care dietary counseling, 65% reverted to normal glucose tolerance, 27% persisted with IGT, and 8% progressed to type 2 diabetes, demonstrating the highly transient nature of IGT in this population.
Effect size65% reversion rate (IGT to NGT)
Follow-up2.9 years
ComparatorAdult IGT cohorts (DPP and ACT-NOW: ~25% reversion rate in adults)
Effect summaryimprovement; 65% reversion rate (IGT to NGT)

Connected entities

Interventions
Natural History
Conditions
Impaired glucose tolerance in obese
Outcomes
reversion to normal glucose tolerance
Populations
Children

Source

PMC6190831
Trajectories of changes in glucose tolerance in a multiethnic cohort of obese youths: An observational prospective analysis
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