ExploreFinding
Finding decline
Among 364 obese youth with normal glucose tolerance at baseline, 14% progressed to impaired glucose tolerance over 2.9 years, with progression characterized by a significant decline in beta-cell function (oral disposition index).
Effect size14% progression rate (NGT to IGT)
Follow-up2.9 years
ComparatorYouth who maintained NGT (86% of baseline NGT group; yearly rate of oDI change did not differ from progressors)
Effect summarydecline; 14% progression rate (NGT to IGT)

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Source

PMC6190831
Trajectories of changes in glucose tolerance in a multiethnic cohort of obese youths: An observational prospective analysis
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