Polycystic Ovary Syndrome

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Adding metformin to lifestyle therapy did not significantly improve ovulation rates compared to placebo plus lifestyle in obese women with PCOS, with an ovulation rate ratio of 2.5 (95% CI: 0.9, 6.6;

Effect: null; ovulation rate ratio 2.5 (whether ovulated), 1.2 (number of ovulations given ovulation); CI: 95% CI: (0.9, 6.6) for whether ovulated; 95% CI: (0

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO

Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had f

Effect: adverse; 6 MET dropouts for medication side effects vs 0 PBO