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Finding
Finding
adverse
Metformin caused significantly more diarrhea and headaches compared to placebo, with 6 dropouts in the metformin arm due to medication side effects versus none in placebo, though metformin users had fewer bladder infections and musculoskeletal complaints.
| Effect size | 6 MET dropouts for medication side effects vs 0 PBO |
| Follow-up | 6 months |
| Comparator | Placebo + identical lifestyle therapy |
| Effect summary | adverse; 6 MET dropouts for medication side effects vs 0 PBO |
| Adverse events | diarrhea more common, headaches more common, 6 dropouts due to medication side effects |
Connected entities
Interventions
Conditions
Populations
Source
PMC3073705
The Effects of Metformin with Lifestyle Therapy in Polycystic Ovary Syndrome: A Randomized Double Blind Study