PREPP: Postpartum Depression Prevention through the Mother-Infant Dyad

Women who received PREPP decreased significantly in clinician-rated depressive symptoms (HRSD) between pre-randomization and 6 weeks postpartum, while ETAU women showed no significant change.

Effect: improvement; B = −6.54

Women who received PREPP decreased significantly in clinician-rated anxiety symptoms (HAM-A) between pre-randomization and 6 weeks postpartum, with effects persisting to 16 weeks, while ETAU women sho

Effect: improvement; B = −7.84

PREPP did not significantly change self-reported depressive symptoms (PHQ-9) between pre-randomization and 6 weeks postpartum, whereas the ETAU group reported significantly more depressive symptoms at

Effect: null; B = .61

Mothers who received PREPP reported significantly fewer bouts of infant fussing and crying at 6 weeks postpartum than mothers in the ETAU group.

Effect: improvement; F (1, 28) = 5.68

All participants randomized to PREPP completed all treatment sessions, yielding a 0% treatment attrition rate, substantially lower than rates reported by many other PPD prevention programs (some with

Effect: improvement; 0% attrition