Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: The Atherosclerosis Risk in Communities Study

For every 5-unit increase in energy-adjusted glycemic index, African Americans had a 1.16-fold increased risk of incident coronary heart disease over 17 years of follow-up.

Effect: decline; HR 1.16; CI: 95% CI:1.01, 1.33

For every 30-unit increase in energy-adjusted glycemic load, Whites had a 1.11-fold increased risk of incident coronary heart disease over 17 years of follow-up.

Effect: decline; HR 1.11; CI: 95% CI:1.01, 1.21

In Whites without diabetes, high glycemic load diet was associated with a 1.14-fold increased risk of incident CHD per 30-unit increase in GL, remaining statistically significant after Bonferroni corr

Effect: decline; HR 1.14; CI: 95% CI:1.02, 1.26

Neither glycemic index nor glycemic load was significantly associated with incident CHD in individuals with type 2 diabetes, in either racial group, although the study was underpowered for this subgro

Effect: null

Among African Americans without diabetes, the hazard ratio for CHD associated with high GI (per 5-unit increase) was 1.16, but did not reach statistical significance.

Effect: null; HR 1.16