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Finding
Finding
decline
For every 5-unit increase in energy-adjusted glycemic index, African Americans had a 1.16-fold increased risk of incident coronary heart disease over 17 years of follow-up.
| Effect size | HR 1.16 |
| CI | 95% CI:1.01, 1.33 |
| Follow-up | 17 years |
| Comparator | Lower glycemic index diet (continuous, per 5-unit decrease in energy-adjusted GI) |
| Effect summary | decline; HR 1.16; CI: 95% CI:1.01, 1.33 |
| Effect modifiers | [{"modifier": "Diabetes status", "interaction_p": "", "direction": "null", "stratum_details": "The interaction between GI and diabetes status was not statistically significant. In stratified analyses, the HR for GI on CHD in African Americans without diabetes was 1.16 but did not reach statistical significance; the HR in African Americans with diabetes was greater than one but also not significant. Small sample sizes in diabetes strata limited power.", "plain_language": "Whether the person had diabetes or not did not statistically change the association between high GI diet and heart disease risk in African Americans, though the study was underpowered to detect this interaction", "annotation_notes": "The paper states 'the interaction between GI or GL and diabetes status was not statistically significant' and 'the sample size in the type 2 diabetes population within race groups was not large enough to bring about statistically significant effect estimates.'"}] |
Connected entities
Interventions
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Outcomes
Populations
Source
PMC3085981
Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: The Atherosclerosis Risk in Communities Study