PMC8176653

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

The association between cardiorespiratory fitness and incident ASCVD was significantly modified by baseline predicted 10-year ASCVD risk (P for interaction <0.001 for composite ASCVD, MI, and stroke),

Effect: improvement; P for interaction <0.001

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35

Among participants with type 2 diabetes and intermediate baseline predicted 10-year ASCVD risk (7.5%-20%), low cardiorespiratory fitness was associated with nearly twice the hazard of ASCVD events com

Effect: improvement; HR 1.94 (low vs high fitness); CI: 95% CI 1.12-3.35