PMC4775391

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

CAC=0 resulted in the largest and most accurate downward risk reclassification among all 13 negative risk markers, consistently regardless of the risk threshold definition used.

Effect: improvement; largest, most accurate downward risk reclassification among all 13 markers

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD

A normal hsCRP level (<2 mg/L) performed poorly as a negative risk marker, providing minimal post-test risk change for both CHD and CVD events, regardless of the cutpoint chosen.

Effect: null; DLR >0.80 for both CHD and CVD