Clinical outcomes of bypass-first versus endovascular-first strategy in patients with chronic limb-threatening ischemia due to infrageniculate arterial disease

Bypass-first revascularization was associated with significantly lower 30-day major amputation compared with endovascular-first strategy in CLTI patients with infrageniculate disease (4.3% vs 7.4%; ad

Effect: improvement; OR 0.60; CI: 95% CI 0.36-0.98

There was no significant difference in adjusted 30-day MALE between bypass-first and endovascular-first revascularization in CLTI patients with infrageniculate disease (9% vs 11.2%; OR 0.73, 95% CI 0.

Effect: null; OR 0.73; CI: 95% CI 0.50-1.08

Bypass-first revascularization was associated with significantly higher 30-day MACE (6.9% vs 2.6%; adjusted OR 3.88, 95% CI 2.18-6.88) and 30-day mortality (3.23% vs 1.8%; adjusted OR 2.77, 95% CI 1.2

Effect: adverse; OR 3.88; CI: 95% CI 2.18-6.88

Bypass-first revascularization was associated with significantly higher 30-day wound complication rates (9.7% vs 3.7%; adjusted OR 2.75, 95% CI 1.71-4.42) and higher blood transfusion or secondary pro

Effect: adverse; OR 2.75; CI: 95% CI 1.71-4.42

After excluding ESRD patients, there was no significant difference in 30-day amputation between bypass-first and endovascular-first revascularization (4.1% vs 6.2%; P=0.1), suggesting the amputation b

Effect: null