First-Year Clinical Outcomes in Gender-Mismatched Heart Transplant Recipients

Heart transplant recipients with male donor-female recipient gender mismatch had significantly more treated acute rejections and were rehospitalized more days during the first post-operative year comp

Effect: decline; Group 3 mean rejections 4.7 vs Group 1 mean 2.8; Group 3 mean rehospitalization 39 days vs Group 1 mean 22 days

Gender-mismatched heart transplant recipients did not have significantly different first-year survival compared to gender-matched recipients, despite both mismatched groups having numerically higher m

Effect: null; Group 2 deaths 22.5% vs Group 3 deaths 17.6% vs Group 1 deaths 13.6%

Diabetes (both pre-existing and new-onset steroid-induced) was a significant risk factor for decreased first-year survival in heart transplant recipients, identified via Cox regression with Bonferroni

Effect: decline