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Finding improvement
Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.
Effect size15% SVR (14/96)
Follow-up24 weeks
ComparatorHistorical rates of 16–31% SVR in prior retreatment studies of HIV/HCV co-infected patients
Effect summaryimprovement; 15% SVR (14/96)

Connected entities

Interventions
Pegylated interferon-α-2a and ribavirin
Conditions
chronic HCV infection
Outcomes
Sustained virological response

Source

PMC2994950
Insulin Resistance Predicts Retreatment Failure in an Efficacy Study of Peginterferon-α-2a and Ribavirin in HIV/HCV Co-infected Patients
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