ExploreInterventionPegylated interferon-α-2a and ribavirin
Intervention

Pegylated interferon-α-2a and ribavirin

Also known as: Pegylated interferon-α-2a 180μg/week subcutaneously + weight-based ribavirin for 48 weeks (retreatment)
6 findings 1 paper 5 related entities View in graph →

Related entities

conditions
outcomes
studys

Findings (50)

None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
adverse

Retreatment with pegIFN-α-2a and ribavirin was associated with significant cytopenias, dose reductions, and discontinuations, including 8% severe adverse events requiring discontinuation within the fi

Effect: adverse; 24% treatment discontinuation (23/96)

Size: 24% treatment discontinuation (23/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)
None
improvement

Retreatment with pegIFN-α-2a and weight-based ribavirin achieved sustained virological response in 15% of HIV/HCV co-infected patients who had previously failed interferon-based therapy.

Effect: improvement; 15% SVR (14/96)

Size: 15% SVR (14/96)

Papers (1)