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Intervention

candesartan

Also known as: 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acid 2-ethoxy-7-carboxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylbenzimidazole Candesartan Candesartan (8-32 mg/day) for 12 months Candesartan (8-32 mg/day) vs lisinopril (10-40 mg/day) vs HCTZ (12.5-25 mg/day) for 12 months Candesartan (product) Candesartan (substance) Candesartan product Candesartan-containing product Product containing candesartan Product containing candesartan (medicinal product) candesartan
12 findings 1 paper 9 related entities View in graph →

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outcomes
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Findings (50)

None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
improvement

Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significan

Effect: improvement; TMT-B improved by 17.1 seconds

Size: TMT-B improved by 17.1 seconds
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6
None
null

All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are

Effect: null; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

Size: Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6

Papers (1)