ExploreFinding
Finding null
All three antihypertensive regimens achieved equivalent systolic blood pressure reductions and blood pressure control rates, establishing that cognitive and hemodynamic differences between groups are not attributable to differential blood pressure lowering.
Effect sizeLisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93
Follow-up12 months
ComparatorThree-way comparison (candesartan vs lisinopril vs HCTZ)
Effect summarynull; Lisinopril: -27±5 mmHg; Candesartan: -26±5 mmHg; HCTZ: -25±6 mmHg; p=0.93

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Source

PMC3608194
Antihypertensive therapy and cerebral hemodynamics in Executive Mild Cognitive Impairment: results of a Pilot randomized clinical trial
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