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Finding improvement
Candesartan produced the greatest improvement in executive function, with TMT Part B improving by 17.1 seconds versus 4.2 seconds for HCTZ and worsening by 14.4 seconds for lisinopril, with significant between-group differences (p=0.008).
Effect sizeTMT-B improved by 17.1 seconds
Follow-up12 months
ComparatorLisinopril (10-40 mg/day) and hydrochlorothiazide (12.5-25 mg/day)
Effect summaryimprovement; TMT-B improved by 17.1 seconds

Connected entities

Interventions
candesartan
Conditions
Mild Cognitive Impairment
Outcomes
Executive Function
Populations
Older Adults

Source

PMC3608194
Antihypertensive therapy and cerebral hemodynamics in Executive Mild Cognitive Impairment: results of a Pilot randomized clinical trial
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