A Randomized Clinical Trial of Cognitive-Behavioral Therapy for Insomnia to Augment PTSD Treatment in Survivors of Interpersonal Violence

At 6 weeks (post-CBTi, pre-CPT), participants in the CBTi condition had significantly greater reductions in insomnia severity compared to the attention control condition, with a large effect size (d =

Effect: improvement; d = 1.0

At 6 weeks, participants receiving CBTi had significantly greater reductions in depression severity (HAM-D) compared to attention control, with a large effect size (d = 0.87), even before beginning PT

Effect: improvement; d = 0.87

At 6 weeks, participants receiving CBTi had significantly greater reductions in PTSD severity (CAPS) compared to attention control, with a moderate effect size (d = 0.51), comparable to the meta-analy

Effect: improvement; d = 0.51

At 20 weeks, sequential CBTi+CPT produced significantly greater reductions in insomnia severity compared to Control+CPT, with higher rates of insomnia remission, treatment response, and no longer meet

Effect: improvement

At 20 weeks, sequential CBTi+CPT produced significantly greater reductions in depression severity compared to Control+CPT. Approximately 46% of CBTi+CPT participants achieved depression remission comp

Effect: improvement

At 20 weeks, CBTi+CPT produced significantly greater reductions in PTSD severity compared to Control+CPT. CAPS scores decreased by approximately 36 points in CBTi+CPT versus approximately 23 points in

Effect: improvement; ~36 point CAPS reduction (CBTi+CPT) vs ~23 point reduction (Control+CPT)

There was little evidence of symptom deterioration at 20 weeks and no differences between conditions. No participants met PTSD or depression deterioration criteria. One participant in each condition m

Effect: null; 1 participant per condition met insomnia deterioration criteria; 0 met PTSD or depression deterioration criteria