Factors affecting achievement of glycemic targets among type 2 diabetes patients in South Asia: analysis of the CARRS Trial
Extracted findings (8)
Adherence to prescribed diet
improvementAdherence to prescribed medications was associated with a 46% higher probability of achieving guideline-recommended glycemic control (HbA1c <7%) in the final multivariate model (RR: 1.46, 95% CI: 1.09
Effect: improvement; RR: 1.46; CI: 95% CI: 1.09, 1.95
Adherence to prescribed diet
improvementAdherence to diet plans was associated with a 79% higher probability of achieving guideline-recommended glycemic control (HbA1c <7%) in the final multivariate model (RR: 1.79, 95% CI: 1.43-2.23), the
Effect: improvement; RR: 1.79; CI: 95% CI: 1.43, 2.23
Adherence to exercise plans was significantly associated with achieving HbA1c <7% in bivariate analysis but was not a significant independent predictor in the final multivariate model adjusting for de
Effect: null
Presence of
declinePresence of microvascular complications at baseline reduced the probability of achieving guideline-recommended glycemic control by 30% (RR: 0.70, 95% CI: 0.53-0.92), indicating that patients with exis
Effect: decline; RR: 0.70; CI: 95% CI: 0.53-0.92
persistent poor glycemic control
declineLonger duration of diabetes (>15 years) was associated with a 41% higher risk of persistently poor glycemic control (HbA1c >9%) compared to shorter duration (RR: 1.41, 95% CI: 1.15-1.72).
Effect: decline; RR: 1.41; CI: 95% CI: 1.15, 1.72
Presence of
declineHyperlipidemia at baseline was associated with a 19% higher risk of persistently poor glycemic control (HbA1c >9%) over the study period (RR: 1.19, 95% CI: 1.06-1.34).
Effect: decline; RR: 1.19; CI: 95% CI: 1.06, 1.34
persistent poor glycemic control
declineThe youngest age group (35-49 years) had persistently worse glycemic control compared to the elderly group (>=65 years), with elderly patients having a 39% lower relative risk of persistent poor contr
Effect: decline; RR: 0.61; CI: 95% CI: 0.47-0.79
Overall, only 16.3% (95% CI: 14.6-18.1) of participants with poorly controlled type 2 diabetes at baseline achieved guideline-recommended glycemic control (HbA1c <7%) over the study period, while 34.9
Effect: decline; 16.3%; CI: 95% CI: 14.6, 18.1