Paperspregnancy7213062

Incidence and Long-Term Outcomes of Hypertensive Disorders of Pregnancy

Journal of the American College of Cardiology · 12-5-2020 · 7213062 on PMC →
Entities in this paper
History of hypertensive retinopathy History of Stroke Multimorbidity Dementia all-cause mortality Syphilitic coronary artery disease incident stroke diagnosis Coronary Artery Disease Cardiac Arrhythmia Chronic Kidney Disease Rate of speech Congestive heart failure incident dementia diagnosis all-cause death incident diagnoses of hypertension, hyperlipidemia, and diabetes

Extracted findings (10)

Women with a history of hypertensive disorders of pregnancy had more than double the risk of subsequent stroke compared to age- and parity-matched women with normotensive pregnancies over a median fol

Effect: decline; HR 2.27; CI: 95% CI 1.37-3.76

Size: HR 2.27 CI: 95% CI 1.37-3.76

Women with a history of hypertensive disorders of pregnancy had nearly double the risk of subsequent coronary artery disease compared to age- and parity-matched women with normotensive pregnancies.

Effect: decline; HR 1.89; CI: 95% CI 1.26-2.82

Size: HR 1.89 CI: 95% CI 1.26-2.82

Women with a history of hypertensive disorders of pregnancy had a 62% higher risk of subsequent cardiac arrhythmias compared to age- and parity-matched women with normotensive pregnancies.

Effect: decline; HR 1.62; CI: 95% CI 1.28-2.05

Size: HR 1.62 CI: 95% CI 1.28-2.05

Women with a history of hypertensive disorders of pregnancy had nearly 2.5 times the risk of subsequent chronic kidney disease compared to age- and parity-matched women with normotensive pregnancies.

Effect: decline; HR 2.41; CI: 95% CI 1.54-3.78

Size: HR 2.41 CI: 95% CI 1.54-3.78

Women with a history of hypertensive disorders of pregnancy experienced accelerated accumulation of multiple chronic conditions compared to age- and parity-matched women with normotensive pregnancies,

Effect: decline; HR 1.25; CI: 95% CI 1.15-1.35

Size: HR 1.25 CI: 95% CI 1.15-1.35

Women with a history of hypertensive disorders of pregnancy had a 69% higher risk of subsequent congestive heart failure compared to age- and parity-matched women with normotensive pregnancies, though

Effect: decline; HR 1.69; CI: 95% CI 1.05-2.72

Size: HR 1.69 CI: 95% CI 1.05-2.72

Women with a history of hypertensive disorders of pregnancy had a 64% higher risk of subsequent dementia compared to age- and parity-matched women with normotensive pregnancies, though this did not su

Effect: decline; HR 1.64; CI: 95% CI 1.06-2.53

Size: HR 1.64 CI: 95% CI 1.06-2.53

All-cause death rates were not different between women with a history of hypertensive disorders of pregnancy and women with normotensive pregnancies despite increased risks for multiple chronic condit

Effect: null; HR 1.06; CI: 95% CI 0.87-1.30

Size: HR 1.06 CI: 95% CI 0.87-1.30
History of
decline

Women with a history of preeclampsia/eclampsia showed similar magnitude of cardiovascular and renal disease risk as the broader HDP group, with CAD and CKD remaining significant after Bonferroni corre

Effect: decline; HR 1.89; CI: 95% CI 1.07-3.33

Size: HR 1.89 CI: 95% CI 1.07-3.33

Women with a history of hypertensive disorders of pregnancy had significantly higher risks of developing hypertension, hyperlipidemia, and diabetes compared to women with normotensive pregnancies, sug

Effect: decline; HR 2.01; CI: 95% CI 1.74-2.33

Size: HR 2.01 CI: 95% CI 1.74-2.33