Gastrostomy Tube Feeding in Extremely Low Birthweight Infants: Frequency, Associated Comorbidities, and Long-term Outcomes
Extracted findings (7)
Bronchopulmonary dysplasia was the strongest neonatal comorbidity associated with gastrostomy tube placement in ELBW infants, with nearly 3-fold increased adjusted odds after controlling for center an
Effect: decline; OR 2.94; CI: 95% CI 2.20-3.92
Severe intraventricular hemorrhage (grade III-IV) or periventricular leukomalacia was significantly associated with gastrostomy tube placement in ELBW infants after adjustment for center and other neo
Effect: decline; OR 2.01; CI: 95% CI 1.54-2.64
Necrotizing enterocolitis was not significantly associated with gastrostomy tube placement in ELBW infants after adjustment for center and other neonatal morbidities, though NEC with short bowel syndr
Effect: null; OR 1.13; CI: 95% CI 0.70-1.81
Gastrostomy tube placement in ELBW infants was associated with a 3-fold increased odds of neurodevelopmental impairment at 18-22 month follow-up, including significantly higher rates of cerebral palsy
Effect: decline; OR 3.19; CI: 95% CI 2.49-4.10
Gastrostomy tube placement in ELBW infants was associated with poor growth at follow-up, with infants having GT showing significantly higher odds of weight, height, and head circumference below the 10
Effect: decline; OR 2.64; CI: 95% CI 2.07-3.36
Gastrostomy tube placement in ELBW infants was associated with a 4-fold increased odds of chronic feeding problems and 2.4-fold increased odds of chronic breathing problems at 18-22 month follow-up.
Effect: decline; OR 4.06; CI: 95% CI 3.12-5.28
Only 32% of ELBW infants with gastrostomy tubes were taking full oral feeds at 18-22 month follow-up. Infants with neurodevelopmental impairment and chronic breathing problems were less likely to have
Effect: mixed; 32% (108/333)