Adolescent affective symptoms and mortality: a fifty-three year follow-up of a British birth cohort study

Severe adolescent affective symptoms were associated with a 61% increase in all-cause premature mortality over 53 years of follow-up compared to those with mild or no symptoms, independent of childhoo

Effect: decline; HR 1.61; CI: 95% CI 1.20-2.15

Moderate adolescent affective symptoms were not associated with increased all-cause mortality compared to mild or no symptoms. Only the severe category (top 10th percentile) showed excess mortality ri

Effect: null

Severe adolescent affective symptoms were associated with increased cardiovascular mortality in sex-adjusted analyses, but this association was attenuated to non-significance after adjustment for all

Effect: decline; SHR 1.92; CI: 95% CI 1.11-3.32

Severe adolescent affective symptoms were associated with more than double the rate of mortality from 'other' causes (predominantly respiratory, digestive, and nervous system diseases), and this assoc

Effect: decline; SHR 2.03; CI: 95% CI 1.07-3.85

Severe adolescent affective symptoms showed a borderline association with cancer mortality in sex-adjusted analyses, but the confidence interval included the null value and the association was attenua

Effect: null; SHR 1.52; CI: 95% CI 1.00-2.31