The risk of preterm birth and growth restriction in pregnancy after cancer

Cervical cancer survivors had a substantially higher risk of preterm birth in their first live singleton birth conceived after diagnosis, with 28% of births delivered before 37 weeks compared to match

Effect: decline; RR=2.8; CI: 95% CI: 2.1, 3.7

Survivors of invasive breast cancer had a modestly higher risk of preterm birth and substantially higher risks of very preterm birth, low birth weight, very low birth weight, and low Apgar scores in t

Effect: decline; RR=1.3; CI: 95% CI: 1.1, 1.7

Leukemia survivors had a higher risk of preterm birth and low birth weight in their first live singleton birth conceived after diagnosis.

Effect: decline; RR=2.1; CI: 95% CI: 1.3, 3.5

Brain cancer survivors had a higher risk of small for gestational age infants, with 15% (16/104) born SGA, though only 1 of 16 SGA infants was small enough to be classified low birth weight at term.

Effect: decline; RR=1.7; CI: 95% CI: 1.1, 2.8

Survivors of extranodal non-Hodgkin lymphoma had higher risks of SGA infants and low birth weight in their first live singleton birth conceived after diagnosis.

Effect: decline; RR=2.3; CI: 95% CI: 1.5, 3.6

Survivors of ductal carcinoma in situ, thyroid cancer, melanoma, and Hodgkin lymphoma did not have higher estimated risks of preterm birth, low birth weight, or small for gestational age infants in th

Effect: null

African-American thyroid cancer survivors had a 17% risk of low birth weight in the first pregnancy conceived after diagnosis, compared with 5% in white survivors, but this largely reflected higher ba

Effect: decline

White women had a higher risk of low birth weight after reproductive cancer than white women without cancer (14% vs 5%), while African-American women did not have an increase in risk associated with c

Effect: mixed