Mortality and virologic outcomes following access to antiretroviral therapy among a cohort of HIV-infected women who received single-dose nevirapine in Lusaka, Zambia
Extracted findings (4)
Patient Access to Records
improvementAccess to an NNRTI-based ART program more than halved mortality among a cohort of HIV-infected women who had previously received single-dose nevirapine for PMTCT, with the reduction remaining signific
Effect: improvement; RH = 0.46; CI: 95% CI: 0.23-0.91
NNRTI-based ART initiation
improvementAmong SDNVP-exposed women initiating NNRTI-based ART, the proportion achieving viral suppression increased significantly with longer time since SDNVP exposure, from 37.5% at <6 months to 77.1% at >24
Effect: improvement; chi-square trend p=0.01
HIV screening
improvementAmong 1,378 HIV-infected women enrolled during pregnancy, 38.3% met ART eligibility criteria (CD4 <200 or <350 with WHO stage III) during pregnancy, and this group had 23.7% mortality by 24 months in
Effect: improvement; 38.3%
NNRTI-based ART
declineLess than half of HIV-infected women who were in need of ART actually received it when offered, with attrition occurring at screening uptake (20% refused), ART initiation (20% of eligible did not star
Effect: decline