Explore ›
Finding
Finding
decline
More depression symptoms were associated with greater frequency of poly-substance use over time, with effects moderated by gender (significant for males but not females for poly-substance and marijuana use), and depression was specifically associated with cigarette and marijuana use but not alcohol use at baseline.
| Effect size | beta = .05, t(7726) = 4.24 |
| Comparator | Lower depression symptoms within cohort (continuous predictor in multi-level model) |
| Effect summary | decline; beta = .05, t(7726) = 4.24 |
| Effect modifiers | [{"modifier": "Gender (male vs female)", "interaction_p": "p < .001 for poly-substance use; p < .001 for marijuana use", "direction": "attenuates", "stratum_details": "Poly-substance: males beta=.11, t(3196)=6.35, p<.001; females beta=-.03, t(4458)=-1.70, p=.09. Marijuana: males beta=.13, t(3218)=7.61, p<.001; females beta=.00, t(4464)=-0.04, p=.97.", "plain_language": "Depression predicted increased poly-substance and marijuana use for males but not for females", "annotation_notes": "Gender interaction significant for poly-substance and marijuana use. Not significant for cigarette or alcohol use."}, {"modifier": "Developmental stage (adolescence vs young adulthood) for alcohol", "interaction_p": "significant for alcohol use (Table 3)", "direction": "reverses", "stratum_details": "Alcohol: adolescence depression not related (beta=.03, t(4588)=1.80, p=.07); young adulthood more depression associated with LESS alcohol use (beta=-.04, t(3101)=-2.18, p=.03).", "plain_language": "Depression did not predict alcohol use in teens, and surprisingly, more depressed young adults actually drank less alcohol \u2014 possibly because they were isolating themselves from social drinking situations", "annotation_notes": "Interesting reversal: in young adulthood, depression was associated with less (not more) alcohol use. Authors speculate depressed young adults may isolate from social situations that facilitate drinking."}] |
Connected entities
Interventions
Conditions
Outcomes
Populations
Source
PMC8120743
Risk Factors for Alcohol, Marijuana, and Cigarette Polysubstance Use During Adolescence and Young Adulthood: A 7-Year Longitudinal Study of Youth at High Risk for Smoking Escalation