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Finding decline
In the Nurses' Health Study, weight gain showed a dose-response relationship with saccharin intake over 8 years: 54% higher in the highest intake group vs none from 1978-1980, and 34% higher from 1980-1984.
Effect size54% higher weight gain in highest saccharin intake vs none (1978-1980); 34% higher (1980-1984)
Follow-up8 years
ComparatorNon-users of saccharin
Effect summarydecline; 54% higher weight gain in highest saccharin intake vs none (1978-1980); 34% higher (1980-1984)

Connected entities

Interventions
Saccharin
Conditions
Obesity
Outcomes
Weight Gain

Source

PMC5045440
Low-calorie sweetener use and energy balance: Results from experimental studies in animals, and large-scale prospective studies in humans
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