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Finding adverse
Live birth rate per embryo transfer trended higher in the low-dose FSH group (9/15, 60%) compared with the high-dose group (2/11, 18%, P=0.051), and ROC curve analysis validated 150 IU as the optimal cutoff value for starting FSH dose based on live birth rate.
Effect sizeLBR 2/11 (18%) HD vs 9/15 (60%) LD
ComparatorLow-dose FSH (150 IU starting dose, mean total 1,128 IU) combined with letrozole 5 mg/day
Effect summaryadverse; LBR 2/11 (18%) HD vs 9/15 (60%) LD

Connected entities

Interventions
FSH combined with letrozole for ovarian stimulation
Conditions
Breast Cancer
Outcomes
Live Birth
Populations
Postmenopausal Women

Source

PMC3777251
Does higher starting dose of FSH stimulation with letrozole improve fertility preservation outcomes in women with breast cancer?
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