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Finding
Finding
null
Higher starting dose of FSH with letrozole did not yield significantly more oocytes (13.3 +/- 8.7 vs 12.3 +/- 8.0) or embryos (6.3 +/- 4.7 vs 5.4 +/- 3.8) compared to low-dose FSH, despite producing more follicles >17 mm (5.0 +/- 2.0 vs 3.4 +/- 1.4).
| Effect size | 13.3 vs 12.3 oocytes (HD vs LD) |
| Comparator | Low-dose FSH (150 IU starting dose, mean total 1,128 IU) combined with letrozole 5 mg/day |
| Effect summary | null; 13.3 vs 12.3 oocytes (HD vs LD) |
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Source
PMC3777251
Does higher starting dose of FSH stimulation with letrozole improve fertility preservation outcomes in women with breast cancer?