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Finding
Finding
null
Metformin plus lifestyle produced significant weight loss from baseline (-3.4 kg, 95% CI: -5.3, -1.5) at 6 months, but this was not significantly different from placebo plus lifestyle, indicating no additive weight loss benefit from metformin.
| Effect size | -3.4 kg from baseline in MET at 6 months |
| CI | 95% CI: (-5.3, -1.5) |
| Follow-up | 6 months |
| Comparator | Placebo + identical lifestyle therapy |
| Effect summary | null; -3.4 kg from baseline in MET at 6 months; CI: 95% CI: (-5.3, -1.5) |
Connected entities
Interventions
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Outcomes
Populations
Source
PMC3073705
The Effects of Metformin with Lifestyle Therapy in Polycystic Ovary Syndrome: A Randomized Double Blind Study