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Finding
Finding
improvement
Women who lost 5% to less than 10% of body weight had 3.7 times the odds of achieving at least a 70% reduction in total urinary incontinence episodes compared with women who gained weight at 12 months, and 2.4 times the odds at 18 months. Larger weight losses of 10% or more did not provide additional benefit beyond the 5-10% threshold.
| Effect size | OR 3.7 |
| CI | 95% CI 1.4-9.6 |
| Follow-up | 18 months |
| Comparator | Women who gained weight (reference group; gained average 2.1-3.5 kg) |
| Effect summary | improvement; OR 3.7; CI: 95% CI 1.4-9.6 |
| Effect modifiers | [{"modifier": "Baseline BMI (less than 35 vs more than 35)", "interaction_p": "", "direction": "null", "stratum_details": "No significant interaction between baseline BMI and weight change categories for any UI measure", "plain_language": "Weight loss helps incontinence regardless of whether you start at a lower or higher weight", "annotation_notes": "Tested as interaction term in GEE models"}, {"modifier": "Baseline urinary incontinence frequency", "interaction_p": "", "direction": "null", "stratum_details": "No significant interaction between baseline UI frequency and weight change categories", "plain_language": "Weight loss helps whether you leak a lot or a little to start with", "annotation_notes": "Tested as interaction term in GEE models"}] |
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Source
PMC3038422
Improving Urinary Incontinence in Overweight and Obese Women Through Modest Weight Loss