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SSRI pharmacotherapy

Also known as: High-dose SSRI pharmacotherapy (fluoxetine 60-80mg equivalents) for 8-13 weeks High-dose SSRI pharmacotherapy (fluoxetine 60-80mg, sertraline 200mg, paroxetine 60mg, citalopram 60mg, escitalopram 20mg, fluvoxamine 250mg equivalents) for 8-13 weeks Medium-dose SSRI pharmacotherapy (fluoxetine 40mg, sertraline 100mg, paroxetine 40mg, citalopram 40mg, escitalopram 10mg, fluvoxamine 150mg equivalents) for 8-13 weeks SSRI pharmacotherapy at any dose (low, medium, or high) for 8-13 weeks SSRI
12 findings 1 paper 5 related entities View in graph →

Related entities

conditions
Obsessive-Compulsive Disorder4
outcomes
OCD symptom severity2 All-cause dropout rate1 Dropout rate due to side effects1
studys
PMC28889284

Findings (50)

None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
improvement

High-dose SSRI pharmacotherapy showed significantly greater improvement in Y-BOCS score than both low-dose (WMD=2.1, p<0.001) and medium-dose (WMD=1.8, p=0.001) SSRI, and higher treatment response rat

Effect: improvement; WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD=0.22 (95% CI: 0.16-0.28) for treatment response vs placebo; CI: 95% CI: 2.9-4

Size: WMD=3.9 (95% CI: 2.9-4.9) vs placebo for Y-BOCS change; ARD= CI: 95% CI: 2.9-4.9 (Y-BOCS WMD vs placebo);
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →
None
null

Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.

Effect: null; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Size: WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response) CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -
PMC2888928
Finding details → · Paper → · Graph →

Papers (1)