ExploreFinding
Finding null
Medium-dose SSRI pharmacotherapy failed to show significantly greater improvement in Y-BOCS score or treatment response rate compared to low-dose SSRI pharmacotherapy in the treatment of OCD.
Effect sizeWMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response)
CI95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)
Follow-up8-13 weeks
ComparatorLow-dose SSRI pharmacotherapy (fluoxetine 20mg, sertraline 50mg equivalents)
Effect summarynull; WMD=0.4 (Y-BOCS change); ARD=0.01 (treatment response); CI: 95% CI: -0.5-1.4 (Y-BOCS WMD); 95% CI: -0.06-0.07 (ARD)

Connected entities

Interventions
Conditions
Outcomes

Source

PMC2888928
Meta-Analysis of the Dose-Response Relationship of SSRI in Obsessive-Compulsive Disorder
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