ExploreInterventionALL chemotherapy protocol
Intervention

ALL chemotherapy protocol

Also known as: DFCI 05-001 ALL chemotherapy protocol (multi-agent remission induction followed by risk-adapted post-induction therapy, 24 months total) in Hispanic vs non-Hispanic children DFCI 05-001 ALL chemotherapy protocol in Hispanic vs non-Hispanic children DFCI 05-001 ALL chemotherapy protocol in Hispanic vs non-Hispanic children aged < 10 years DFCI 05-001 ALL chemotherapy protocol in Hispanic vs non-Hispanic children aged >= 10 years ALL
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Findings (50)

None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
null

There was no significant difference in infection rates during induction or post-induction therapy between Hispanic and non-Hispanic children treated for ALL on DFCI 05-001.

Effect: null; Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p=0.92

Size: Induction: 25% vs 29%, p=0.36; Post-induction: 31% vs 32%, p
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76
None
improvement

Hispanic patients aged 10 years and older treated for ALL on DFCI 05-001 had a significantly lower cumulative incidence of osteonecrosis compared to non-Hispanic patients, remaining significant in mul

Effect: improvement; HR 0.28; CI: 95% CI 0.10-0.76

Size: HR 0.28 CI: 95% CI 0.10-0.76

Papers (1)