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Finding
Finding
decline
Aortic stenosis was significantly associated with an increased risk of recurrent myocardial infarction in MI patients treated with DAPT, with consistent results across Sweden and Denmark.
| Effect size | HR 1.78 |
| CI | 95% CI 1.25-2.54 |
| Comparator | MI patients without aortic stenosis treated with DAPT |
| Effect summary | decline; HR 1.78; CI: 95% CI 1.25-2.54 |
| Effect modifiers | [{"modifier": "revascularization (PCI subgroup)", "interaction_p": "", "direction": "null", "stratum_details": "PCI subgroup: Sweden HR 2.19 (95% CI 1.58-3.03), Denmark HR 1.62 (95% CI 1.24-2.12). Results remained similar in the revascularized subgroup.", "plain_language": "The increased risk of recurrent heart attack in AS patients persisted even among those who had coronary stenting, suggesting AS itself contributes to the risk beyond just blocked arteries.", "annotation_notes": "Sensitivity analysis in PCI subgroup showed consistent results."}] |
Connected entities
Interventions
Conditions
Outcomes
Source
PMC6717510
Outcomes associated with dual antiplatelet therapy after myocardial infarction in patients with aortic stenosis