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Finding decline
Higher baseline sE-selectin was the most robust biomarker predictor of incident diabetes in the placebo group, remaining significant after adjustment for traditional diabetes risk factors, 1-year changes in risk factors, and all other biomarkers.
Effect sizeHR 1.19
CI95% CI 1.06, 1.34
Follow-up1 year
Comparatorper 1 SD increase in baseline sE-selectin (placebo/standard care group)
Effect summarydecline; HR 1.19; CI: 95% CI 1.06, 1.34

Connected entities

Interventions
E-selectin level
Conditions
Alloxan Diabetes
Outcomes
Risk of

Source

PMC6456055
Non-traditional biomarkers and incident diabetes in the Diabetes Prevention Program: comparative effects of lifestyle and metformin interventions
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