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Finding
Finding
improvement
The addition of a progressive multimodal rehabilitation program to usual care physical therapy significantly improved ventilator weaning success in ICU survivors with acquired weakness, with 87% of the MRP+UC group weaning successfully compared to 41% in the usual care group.
| Effect size | 87% vs. 41% |
| Follow-up | 8 weeks |
| Comparator | Usual care physical therapy alone (LTACH PTs providing basic rehabilitation activities without systematic progression or physiologic monitoring of intensity) |
| Effect summary | improvement; 87% vs. 41% |
| Effect modifiers | [{"modifier": "Baseline ambulatory status", "interaction_p": "p = 0.07", "direction": "amplifies", "stratum_details": "Ambulatory patients at baseline: MRP+UC 100% weaned (7/7) vs UC 50% (3/6)", "plain_language": "Patients who could already walk at baseline got even more benefit from the program for weaning off the ventilator, though this subgroup comparison did not reach significance.", "annotation_notes": "Post-hoc subgroup analysis. Small numbers limit interpretation."}] |
Connected entities
Interventions
Conditions
Outcomes
Source
PMC6143437
A multimodal rehabilitation program for patients with ICU acquired weakness improves ventilator weaning and discharge home