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Finding improvement
Women receiving pharmacotherapy with methadone or buprenorphine had statistically significantly lower opioid overdose rates compared to women not receiving pharmacotherapy at 4-6 months postpartum (1.3 vs 10.7 per 100,000 person-days).
Effect size1.3 per 100,000 person-days on pharmacotherapy vs 10.7 per 100,000 person-days not on pharmacotherapy at 4-6 months postpartum
CI95% CI 0.16-4.74 (on pharmacotherapy); 95% CI 6.84-15.88 (not on pharmacotherapy)
Follow-up4-6 months
Comparatorwomen with evidence of OUD not receiving pharmacotherapy (methadone or buprenorphine) in the same time period
Effect summaryimprovement; 1.3 per 100,000 person-days on pharmacotherapy vs 10.7 per 100,000 person-days not on pharmacotherapy at 4-6 months postpartum; CI: 95% CI 0.16-4.74 (on pharmacotherapy); 95% CI 6.84-15.88 (not on pharmacotherapy)

Connected entities

Interventions
pharmacotherapy for opioid use disorder
Conditions
Opioid Use Disorder
Outcomes
Rate of speech
Populations
Pregnant Women

Source

PMC6060005
Fatal and Nonfatal Overdose Among Pregnant and Postpartum Women in Massachusetts
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