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Finding decline
Long-term survivors of childhood ALL treated with chemotherapy only had significantly higher rates of self-reported inattention (27.9%) and parent-reported attention problems (23.6%) compared to the 10% population expectation, despite ADHD diagnostic rates being comparable to the general population.
Effect size27.9% impaired (self-report inattention) and 23.6% impaired (parent-report attention problems) vs 10% expected
CI95% CI 21.0-35.7% (self-report inattention); 95% CI 17.2-31.0% (parent-report attention problems)
ComparatorPopulation normative data (expected 10% impairment rate, >90th percentile T-score cutoff)
Effect summarydecline; 27.9% impaired (self-report inattention) and 23.6% impaired (parent-report attention problems) vs 10% expected; CI: 95% CI 21.0-35.7% (self-report inattention); 95% CI 17.2-31.0% (parent-report attention problems)

Connected entities

Interventions
Chemotherapy-only treatment for childhood ALL
Conditions
childhood acute lymphoblastic leukemia
Outcomes
Inattention and attention problems
Populations
Children

Source

PMC5986588
Behavioral Symptoms and Psychiatric Disorders in Child and Adolescent Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia Treated with Chemotherapy Only
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