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Finding
Finding
improvement
A coronary artery calcium score of zero was the strongest negative risk marker for ruling out future cardiovascular disease events over 10 years, resulting in a mean 46% relative reduction in pre-test to post-test CVD risk.
| Effect size | DLR 0.54 (SD 0.12) for CVD; DLR 0.49 (0.10) in men, 0.59 (0.12) in women |
| Follow-up | 10 years |
| Comparator | Pre-test risk based on traditional CVD risk factors alone without knowledge of CAC result |
| Effect summary | improvement; DLR 0.54 (SD 0.12) for CVD; DLR 0.49 (0.10) in men, 0.59 (0.12) in women |
| Effect modifiers | [{"modifier": "pre-test ASCVD risk level", "interaction_p": "", "direction": "attenuates", "stratum_details": "DLR for CVD: 0.47 (0.08) in high risk vs 0.67 (0.09) in low risk participants", "plain_language": "CAC=0 was more informative for higher-risk patients. Most people with a pre-test risk up to 15% would shift below 7.5% after a zero calcium score.", "annotation_notes": ""}] |
Connected entities
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Outcomes
Source
PMC4775391
Role of Coronary Artery Calcium Score of Zero and Other Negative Risk Markers for Cardiovascular Disease: The Multi-Ethnic Study Of Atherosclerosis (MESA)