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Finding
Finding
decline
Prenatal methamphetamine exposure was associated with increased variability in reaction time with longer interstimulus intervals on the K-CPT, indicating less consistent attention when the child has to wait longer between stimuli.
| Comparator | Unexposed comparison children (n=148) — mothers denied methamphetamine use during pregnancy and had a negative meconium GC/MS screen |
| Effect summary | decline |
| Effect modifiers | [{"modifier": "Gender", "interaction_p": "p<0.05", "direction": "amplifies", "stratum_details": "Gender was associated with an increase in Hit Standard Error ISI Change (P<0.05)", "plain_language": "Gender was associated with greater variability in reaction time, though the paper does not specify which gender", "annotation_notes": "Gender listed as significant covariate for Hit Standard Error ISI Change."}, {"modifier": "Caretaker change", "interaction_p": "p<0.05", "direction": "attenuates", "stratum_details": "Caretaker change was associated with a decrease in Hit Standard Error ISI Change (P<0.05)", "plain_language": "Children who experienced a change in caretaker showed less attention variability", "annotation_notes": ""}] |
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Source
PMC3800474
The Effect of Prenatal Methamphetamine Exposure on Attention as Assessed by Continuous Performance Tests: Results from the Infant Development, Environment, and Lifestyle (IDEAL) Study