ExploreFinding
Finding improvement
CBT significantly improved general mental health quality of life compared with enhanced usual care in older adults with GAD in primary care (MCS 49.6 vs 45.3, p=.008), with gains maintained over 12-month follow-up.
Effect sizeMCS 49.6 vs 45.3
CI95% CI 47.4 to 51.8 (CBT) vs 95% CI 42.6 to 47.9 (EUC)
Follow-up12 months
ComparatorEnhanced usual care (biweekly supportive phone calls for 3 months plus routine primary care)
Effect summaryimprovement; MCS 49.6 vs 45.3; CI: 95% CI 47.4 to 51.8 (CBT) vs 95% CI 42.6 to 47.9 (EUC)
Effect modifiers[{"modifier": "treatment expectancy", "interaction_p": "", "direction": "attenuates", "stratum_details": "When treatment expectancy added as covariate, MCS group difference only approached significance (p=.04)", "plain_language": "Part of the mental health quality-of-life improvement from CBT may reflect higher expectations rather than the therapy itself. Accounting for expectations made the benefit borderline.", "annotation_notes": "MCS p=.008 without expectancy, p=.04 with expectancy covariate (still borderline significant at alpha=.025)"}]

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Source

PMC3328789
Cognitive Behavior Therapy for Generalized Anxiety Disorder Among Older Adults in Primary Care: A Randomized Clinical Trial
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