ExploreFinding
Finding improvement
CBT significantly improved coexistent depressive symptoms compared with enhanced usual care in older adults with GAD in primary care (BDI 10.2 vs 12.8, p=.02), with gains maintained over 12-month follow-up.
Effect sizeBDI 10.2 vs 12.8
CI95% CI 8.5 to 11.9 (CBT) vs 95% CI 10.5 to 15.1 (EUC)
Follow-up12 months
ComparatorEnhanced usual care (biweekly supportive phone calls for 3 months plus routine primary care)
Effect summaryimprovement; BDI 10.2 vs 12.8; CI: 95% CI 8.5 to 11.9 (CBT) vs 95% CI 10.5 to 15.1 (EUC)
Effect modifiers[{"modifier": "treatment expectancy", "interaction_p": "", "direction": "attenuates", "stratum_details": "When treatment expectancy added as covariate, BDI group difference only approached significance (p=.05)", "plain_language": "The depression improvement from CBT may partly reflect that CBT patients expected more improvement. When accounting for expectations, the depression benefit became borderline.", "annotation_notes": "Unlike PSWQ (p<.001 after expectancy adjustment), BDI group difference weakened to p=.05 with expectancy covariate"}]

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Source

PMC3328789
Cognitive Behavior Therapy for Generalized Anxiety Disorder Among Older Adults in Primary Care: A Randomized Clinical Trial
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