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Finding mixed
The relationship between on-treatment diastolic blood pressure and primary outcome in very old hypertensive CAD patients follows a J-shaped curve, with the hazard ratio nadir at 70 mm Hg -- somewhat lower than the 75 mm Hg nadir observed for all other age groups.
Effect sizeHR nadir at DBP 70 mm Hg for very old (vs 75 mm Hg for all other age groups)
ComparatorSame cohort at different on-treatment diastolic blood pressure levels (reference DBP = 90 mm Hg, HR = 1.0)
Effect summarymixed; HR nadir at DBP 70 mm Hg for very old (vs 75 mm Hg for all other age groups)

Connected entities

Interventions
Antihypertensive
Conditions
Hypertension
Outcomes
Primary composite outcome
Populations
Older Adults

Source

PMC3008373
Blood Pressure and Outcomes in Very Old Hypertensive Coronary Artery Disease Patients: An INVEST Substudy
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