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Finding improvement
In the pre-planned subgroup of infants born at <= 34 weeks, rescue antenatal steroids produced a more pronounced Crs benefit (~30% increase, 1.17 vs 0.90 mL/cm H2O/kg, p=0.0395) with significantly less RDS, less need for >= 30% and >= 40% oxygen compared to placebo.
Effect size1.17 versus 0.90 mL/cm H2O/kg
CIadjusted 95% CI for difference: 0.02 to 0.60
ComparatorPlacebo (identical-appearing injections containing 25 mg cortisone acetate)
Effect summaryimprovement; 1.17 versus 0.90 mL/cm H2O/kg; CI: adjusted 95% CI for difference: 0.02 to 0.60

Connected entities

Interventions
Betamethasone
Conditions
Respiratory distress syndrome
Outcomes
Respiratory compliance
Populations
Children

Source

PMC2878893
Respiratory Compliance in Preterm Infants after a Single Rescue Course of Antenatal Steroids: A Randomized Controlled Trial
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