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Finding
Finding
improvement
Preterm infants randomized to a single rescue course of antenatal steroids had significantly increased respiratory compliance compared to placebo (1.21 vs 1.01 mL/cm H2O/kg, about 20% increase, p=0.0433), measured within 72 hours of birth.
| Effect size | 1.21 versus 1.01 mL/cm H2O/kg |
| CI | adjusted 95% CI 0.01, 0.49 |
| Comparator | Placebo (identical-appearing injections containing 25 mg cortisone acetate, an inactive steroid) |
| Effect summary | improvement; 1.21 versus 1.01 mL/cm H2O/kg; CI: adjusted 95% CI 0.01, 0.49 |
| Effect modifiers | [{"modifier": "Gestational age at delivery (<= 34 weeks)", "interaction_p": "", "direction": "amplifies", "stratum_details": "Subgroup born <= 34 weeks showed greater Crs benefit (~30% increase, 1.17 vs 0.90 mL/cm H2O/kg, p=0.0395) compared to ~20% in total population", "plain_language": "", "annotation_notes": ""}] |
Connected entities
Interventions
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Populations
Source
PMC2878893
Respiratory Compliance in Preterm Infants after a Single Rescue Course of Antenatal Steroids: A Randomized Controlled Trial