|
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
|
Lancet (London, England) |
2015 |
778.8 |
6,471 |
|
Analysis of shared heritability in common disorders of the brain
|
Science (New York, N.Y.) |
2018 |
197.4 |
2,002 |
|
The International Federation of Gynecology and Obstetrics (FIGO) Initiative on Preeclampsia (PE): A Pragmatic Guide for First Trimester Screening and Prevention
|
International journal of gynaecology and |
2019 |
80.3 |
1,127 |
|
Acupuncture for chronic pain: update of an individual patient data meta-analysis
|
The journal of pain : official journal o |
2018 |
75.7 |
803 |
|
Sex-specific physiology and cardiovascular disease
|
Advances in experimental medicine and bi |
2018 |
60.5 |
167 |
|
Acupuncture for the prevention of episodic migraine
|
The Cochrane database of systematic revi |
2016 |
58.6 |
286 |
|
Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents
|
The Cochrane database of systematic revi |
2015 |
51.8 |
249 |
|
Leptospirosis in Humans
|
Current topics in microbiology and immun |
2015 |
50.3 |
945 |
|
Evidence-based Evaluation of Complementary Health Approaches for Pain Management in the United States
|
Mayo Clinic proceedings |
2016 |
48.9 |
249 |
|
Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1
|
The New England journal of medicine |
2015 |
48.1 |
466 |
|
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
|
The New England journal of medicine |
2016 |
47.4 |
882 |
|
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats
|
Nature medicine |
2016 |
45.8 |
1,001 |
|
Blocking neuronal signaling to immune cells treats streptococcal invasive infection
|
Cell |
2018 |
37.9 |
416 |
|
Acupuncture for the prevention of tension-type headache
|
The Cochrane database of systematic revi |
2016 |
37.4 |
204 |
|
Selumetinib in Children with BRAF-Aberrant or Neurofibromatosis type 1-Associated Recurrent, Refractory or Progressive Low-Grade Glioma: a Multi-Center Phase II Trial
|
The Lancet. Oncology |
2019 |
36.5 |
485 |
|
Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials
|
Lancet (London, England) |
2018 |
34.8 |
300 |
|
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure
|
The New England journal of medicine |
2019 |
34.1 |
455 |
|
Update on Medical Overuse
|
JAMA internal medicine |
2016 |
33.9 |
103 |
|
Neuropsychiatric lupus: new mechanistic insights and future treatment directions
|
Nature reviews. Rheumatology |
2019 |
31.0 |
411 |
|
Migraine and the trigeminovascular system—40 years and counting
|
The Lancet. Neurology |
2019 |
30.4 |
644 |
|
Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial
|
Lancet (London, England) |
2018 |
30.0 |
434 |
|
Binge-Eating Disorder in Adults A Systematic Review and Meta-analysis
|
Annals of internal medicine |
2016 |
29.6 |
283 |
|
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis
|
The New England journal of medicine |
2018 |
23.6 |
278 |
|
Benralizumab for PDGFRA -Negative Hypereosinophilic Syndrome
|
The New England journal of medicine |
2019 |
22.7 |
211 |
|
A randomized placebo-controlled phase 1 safety and tolerability study of a novel human anti-MERS coronavirus polyclonal intravenous immunoglobulin produced from transchromosomic cattle
|
The Lancet. Infectious diseases |
2018 |
20.8 |
115 |
|
Borrelia miyamotoi Infection in Nature and in Humans
|
Clinical microbiology and infection : th |
2015 |
20.1 |
257 |
|
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis
|
The Cochrane database of systematic revi |
2015 |
19.9 |
251 |
|
Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment
|
Cortex; a journal devoted to the study o |
2016 |
16.6 |
433 |
|
Larazotide Acetate for Persistent Symptoms of Celiac Disease Despite a Gluten-Free Diet: A Randomized Controlled Trial
|
Gastroenterology |
2015 |
16.0 |
259 |
|
Multiple Past Concussions in High School Football Players Are There Differences in Cognitive Functioning and Symptom Reporting?
|
The American journal of sports medicine |
2016 |
15.7 |
92 |
|
C alcitonin G ene -R elated P eptide (CGRP) A New Target for Migraine
|
Annual review of pharmacology and toxico |
2015 |
14.5 |
401 |
|
Osteoarthritis Year in Review 2015: Biology
|
Osteoarthritis and cartilage / OARS, Ost |
2016 |
14.2 |
161 |
|
Sleep, emotional distress, and physical health in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
|
Psycho-oncology |
2019 |
14.2 |
67 |
|
Factors Associated With Concussion-like Symptom Reporting in High School Athletes
|
JAMA pediatrics |
2015 |
13.7 |
251 |
|
The Rickettsioses: A Practical Update
|
Infectious disease clinics of North Amer |
2019 |
13.1 |
228 |
|
Effect of Oral Eliglustat vs Placebo on Spleen Volume in Patients with Splenomegaly and Gaucher Disease Type 1: The ENGAGE Randomized Clinical Trial
|
JAMA |
2015 |
12.8 |
154 |
|
Safety of Noninvasive Brain Stimulation in Children and Adolescents
|
Brain stimulation |
2015 |
12.7 |
294 |
|
Leptomeningeal metastasis from systemic cancer: review and update on management.
|
Cancer |
2018 |
12.7 |
254 |
|
Perceived triggers of primary headache disorders: A meta-analysis
|
Cephalalgia : an international journal o |
2018 |
12.6 |
313 |
|
Cytoreduction for Colorectal Metastases: Liver, Lung, Peritoneum, Lymph Nodes, Bone, Brain. When Does it Palliate, Prolong Survival, and Potentially Cure?
|
Current problems in surgery |
2018 |
12.6 |
287 |
|
Comorbid Symptoms of Emotional Distress in Adult Survivors of Childhood Cancer
|
Cancer |
2016 |
12.4 |
47 |
|
Structure and Function of Serotonin G protein Coupled Receptors
|
Pharmacology & therapeutics |
2015 |
12.1 |
361 |
|
Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial
|
The Lancet. Neurology |
2015 |
11.9 |
250 |
|
Near Point of Convergence After a Sport-Related Concussion Measurement Reliability and Relationship to Neurocognitive Impairment and Symptoms
|
The American journal of sports medicine |
2015 |
11.8 |
192 |
|
Validation of Patient-Reported Outcomes Measurement Information System (PROMIS) computerized adaptive tests in cervical spine surgery
|
Journal of neurosurgery. Spine |
2018 |
11.5 |
117 |
|
Sleep Disorders and Migraine: Review of Literature and Potential Pathophysiology Mechanisms
|
Headache |
2018 |
11.4 |
220 |
|
Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies
|
CNS drugs |
2018 |
10.8 |
258 |
|
Neurovascular contributions to migraine: moving beyond vasodilation
|
Neuroscience |
2016 |
10.8 |
216 |
|
Autonomic Dysreflexia after Spinal Cord Injury: Systemic Pathophysiology and Methods of Management
|
Autonomic neuroscience : basic & clinica |
2018 |
10.8 |
267 |
|
Physical Activity Level and Symptom Duration Are Not Associated After Concussion
|
The American journal of sports medicine |
2016 |
10.7 |
76 |
|
Pharmacokinetics and Safety of High-Dose Intravenous Valproic Acid in Healthy Subjects: A Dose Escalation Trial To Support Clinical Translational Studies
|
Clinical pharmacokinetics |
2018 |
10.6 |
52 |
|
Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study
|
The lancet. Gastroenterology & hepatolog |
2016 |
10.0 |
91 |
|
Transcranial Magnetic Stimulation (TMS) of the Brain: Guidelines for Pain Treatment Research
|
Pain |
2015 |
10.0 |
153 |
|
Out-of-Pocket Expenditures on Complementary Health Approaches Associated with Painful Health Conditions in a Nationally Representative Adult Sample
|
The journal of pain : official journal o |
2015 |
10.0 |
48 |
|
Potentially Addictive Properties of Sugar-Sweetened Beverages among Adolescents
|
Appetite |
2019 |
9.4 |
75 |
|
Glial Injury in Neurotoxicity After Pediatric CD19-Directed Chimeric Antigen Receptor T Cell Therapy
|
Annals of neurology |
2019 |
9.1 |
183 |
|
Frequency of Chronic Joint Pain following Chikungunya Infection: A Colombian Cohort Study
|
Arthritis & rheumatology (Hoboken, N.J.) |
2018 |
8.4 |
110 |
|
Childhood Abuse, Intimate Partner Violence and Risk of Migraine among Pregnant Women: An Epidemiologic Study
|
Headache |
2016 |
8.3 |
29 |
|
The impact of spinal manipulation on migraine pain and disability: A systematic review and meta-analysis
|
Headache |
2019 |
8.2 |
96 |
|
CRAC Channels And Disease – From Human CRAC Channelopathies And Animal Models To Novel Drugs
|
Cell calcium |
2019 |
8.0 |
96 |
|
Investigations on CXCL13 in Anti– N -Methyl-D-Aspartate Receptor Encephalitis A Potential Biomarker of Treatment Response
|
JAMA neurology |
2015 |
7.9 |
171 |
|
Does Mindfulness-Based Cognitive Therapy for Migraine Reduce Migraine-Related Disability in People with Episodic and Chronic Migraine? A Phase 2b Pilot Randomized Clinical Trial
|
Headache |
2019 |
7.9 |
102 |
|
Spontaneous Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis Describing the Diagnostic Accuracy of History, Physical Exam, Imaging, and Lumbar Puncture with an Exploration of Test Thresholds
|
Academic emergency medicine : official j |
2016 |
7.9 |
133 |
|
Childhood Exposure to Violence and Chronic Physical Conditions in a National Sample of US Adolescents
|
Psychosomatic medicine |
2016 |
7.8 |
63 |
|
Complementary and Integrative Medicine for Episodic Migraine: An Update of Evidence from the Last 3 Years
|
Current pain and headache reports |
2019 |
7.6 |
88 |
|
Adjunctive Minocycline in Clozapine Treated Schizophrenia Patients with Persistent Symptoms
|
Journal of clinical psychopharmacology |
2015 |
7.2 |
101 |
|
Inflammatory Mediators of Opioid Tolerance: Implications for Dependency and Addiction
|
Peptides |
2019 |
7.1 |
104 |
|
Metabolic concepts in idiopathic intracranial hypertension and their potential for therapeutic intervention
|
Journal of neuro-ophthalmology : the off |
2018 |
7.0 |
122 |
|
Initial somatic symptoms are associated with prolonged symptom duration following concussion in adolescents
|
Acta paediatrica (Oslo, Norway : 1992) |
2016 |
6.9 |
86 |
|
Safety of the 9-Valent Human Papillomavirus Vaccine
|
Pediatrics |
2019 |
6.8 |
62 |
|
Varicella zoster virus triggers the immunopathology of giant cell arteritis
|
Current opinion in rheumatology |
2016 |
6.7 |
45 |
|
Infant Colic
|
Seminars in pediatric neurology |
2016 |
6.6 |
35 |
|
Safety of hormonal contraceptives among women with migraine: A systematic review ☆
|
Contraception |
2016 |
6.6 |
57 |
|
Psychosocial Factors and Central Sensitivity Syndromes
|
Current rheumatology reviews |
2015 |
6.5 |
193 |
|
Safety and pharmacokinetics of broadly neutralizing human monoclonal antibody VRC07–523LS in healthy adults: A phase 1 dose-escalation clinical trial
|
The lancet. HIV |
2019 |
6.5 |
105 |
|
Cortical spreading depression as a site of origin for migraine: Role of CGRP
|
Cephalalgia : an international journal o |
2019 |
6.3 |
125 |
|
Seizures in supratentorial meningioma: a systematic review and meta-analysis
|
Journal of neurosurgery |
2016 |
6.3 |
178 |
|
Simvastatin and Vitamin D for Migraine Prevention: A Randomized Controlled Trial
|
Annals of neurology |
2015 |
6.3 |
155 |
|
The Chiari Severity Index: A Preoperative Grading System for Chiari Malformation Type 1
|
Neurosurgery |
2015 |
6.3 |
101 |
|
Sex Differences in Response to Ketamine as A Rapidly Acting Intervention for Treatment Resistant Depression
|
Journal of psychiatric research |
2019 |
6.2 |
68 |
|
A NEW DIAGNOSTIC APPROACH TO THE ADULT PATIENT WITH ACUTE DIZZINESS
|
The Journal of emergency medicine |
2018 |
6.2 |
128 |
|
The Insula: A ‘Hub of Activity’ in Migraine
|
The Neuroscientist : a review journal br |
2016 |
6.1 |
147 |
|
A phase 1 study of the safety, reactogenicity, and immunogenicity of a Schistosoma mansoni vaccine with or without glucopyranosyl lipid A aqueous formulation (GLA-AF) in healthy adults from a non-endemic area
|
Vaccine |
2019 |
6.0 |
64 |
|
Structural Determinants of 5-HT 2B Receptor Activation and Biased Agonism
|
Nature structural & molecular biology |
2018 |
6.0 |
171 |
|
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress
|
The journal of pain : official journal o |
2015 |
5.9 |
74 |
|
The Role of Melatonin in the Treatment of Primary Headache Disorders
|
Headache |
2016 |
5.8 |
97 |
|
Segesterone Acetate/Ethinyl Estradiol 12-Month Contraceptive Vaginal System Safety Evaluation
|
Contraception |
2019 |
5.6 |
45 |
|
Evaluation and management of migraine in midlife women
|
Menopause (New York, N.Y.) |
2018 |
5.5 |
45 |
|
Neurostimulation for Treatment of Migraine and Cluster Headache
|
Pain medicine (Malden, Mass.) |
2015 |
5.5 |
93 |
|
Barriers to Behavioral Treatment Adherence for Headache: An Examination of Attitudes, Beliefs, and Psychiatric Factors
|
Headache |
2019 |
5.5 |
63 |
|
TRPM8 and Migraine
|
Headache |
2016 |
5.4 |
94 |
|
Symptomatic suspected gluten exposure is common among patients with coeliac disease on a gluten-free diet
|
Alimentary pharmacology & therapeutics |
2016 |
5.3 |
72 |
|
Polymer-induced central nervous system complications following vascular procedures: spectrum of iatrogenic injuries and review of outcomes ☆ , ★
|
Human pathology |
2016 |
5.1 |
53 |
|
Flunarizine Prevents Hepatitis C Virus Membrane Fusion in a Genotype-dependent Manner by Targeting the Potential Fusion Peptide within E1
|
Hepatology (Baltimore, Md.) |
2016 |
5.1 |
70 |
|
Neuropsychiatric Symptoms and Expenditure on Complementary and Alternative Medicine
|
The Journal of clinical psychiatry |
2015 |
5.0 |
18 |
|
A phase I study of TRC105 anti-endoglin ( CD 105) antibody in metastatic castration-resistant prostate cancer
|
BJU international |
2015 |
4.9 |
58 |
|
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness
|
Pain |
2015 |
4.9 |
100 |
|
Random Forests of Interaction Trees for Estimating Individualized Treatment Effects in Randomized Trials
|
Statistics in medicine |
2018 |
4.9 |
42 |
|
Varicella zoster virus and giant cell arteritis
|
Current opinion in infectious diseases |
2016 |
4.8 |
32 |
|
Anxiety-related adverse events following immunization (AEFI): A systematic review of published clusters of illness
|
Vaccine |
2018 |
4.8 |
57 |