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Finding decline
Opioid overdose rates were lowest in the third trimester (3.3 per 100,000 person-days) then increased sharply in the postpartum period, with the highest rate at 7-12 months after delivery (12.3 per 100,000 person-days), demonstrating the postpartum year as a period of elevated vulnerability.
Effect size3.3 per 100,000 person-days (3rd trimester) rising to 12.3 per 100,000 person-days (7-12 months postpartum)
CI95% CI 1.6-6.1 (3rd trimester); 95% CI 9.9-15.0 (7-12 months postpartum)
Comparatorthird trimester overdose rate as baseline comparison for postpartum trajectory
Effect summarydecline; 3.3 per 100,000 person-days (3rd trimester) rising to 12.3 per 100,000 person-days (7-12 months postpartum); CI: 95% CI 1.6-6.1 (3rd trimester); 95% CI 9.9-15.0 (7-12 months postpartum)
Adverse eventsopioid-related overdose events 8.0 per 100,000 person days, 3.3 per 100,000 person days (3rd trimester), 12.3 per 100,000 person days (7-12 months postpartum)

Connected entities

Interventions
Knowledge level about sexual function during pregnancy and postpartum
Conditions
Opioid Overdose
Outcomes
Rate of speech
Populations
Pregnant Women

Source

PMC6060005
Fatal and Nonfatal Overdose Among Pregnant and Postpartum Women in Massachusetts
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