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Finding
Finding
decline
The TCN2 rs1801198 polymorphism, which was more prevalent in Hispanic patients, was associated with inferior event-free survival within the Hispanic patient cohort in multivariable modeling, and was also associated with increased induction infection risk in Hispanic patients.
| Effect size | HR=3.15 |
| Comparator | Hispanic patients without the target TCN2 genotype |
| Effect summary | decline; HR=3.15 |
| Adverse events | induction infection 32% vs. 11% |
Connected entities
Interventions
Conditions
Outcomes
Populations
Source
PMC5766393
An investigation of toxicities and survival in Hispanic children and adolescents with ALL: Results from the Dana-Farber Cancer Institute ALL Consortium protocol 05-001