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Finding
Finding
improvement
Elderly MDD patients receiving continuation ECT plus medications had significantly higher mental component scores on the SF-36 over 6 months compared to those receiving medications alone, with an 8.2-point advantage at 24 weeks.
| Effect size | 8.2 point advantage (MCS) |
| CI | 95% CI 4.2-12.2 |
| Follow-up | 6 months |
| Comparator | Venlafaxine 225mg/day plus lithium (0.4-0.6 mEq/L) alone (PHARM arm) |
| Effect summary | improvement; 8.2 point advantage (MCS); CI: 95% CI 4.2-12.2 |
| Effect modifiers | [{"modifier": "psychosis status", "interaction_p": "", "direction": "null", "stratum_details": "Treatment interactions for psychosis tested but not reported as significant", "plain_language": "Whether the patient had psychotic features did not change how much mental QOL benefit they got from continuation ECT", "annotation_notes": "Implied null from methods stating interaction was tested but not reported as significant."}] |
Connected entities
Conditions
Populations
Source
PMC5742556
Effects of Continuation Electroconvulsive Therapy on Quality of Life in Elderly Depressed Patients: A Randomized Clinical Trial